OGSA-WebDB/Application

Grid Search for Cancer Prevention Project †

• It is a joint project among National Institute of Advanced Industrial Science and Technology (AIST), Division of Clinical and BioInformatic Engineering (CBIE), and Business Search Technologies Corporation (BST).
• The system accesses and integrates data from four Web databases: JSNPs ( http://snp.ims.u-tokyo.ac.jp/ ), OMIM ( http://www.ncbi.nlm.nih.gov/omim/ ), Pubmed (http://www.ncbi.nlm.nih.gov/books/bv.fcgi ) and PharmGKB ( http://http://www.pharmgkb.org/ ).
• For details, see: http://www.ggf.org/GGF17/materials/276/BST-WebDB_0512-final.ppt

• Demonstration server for this application is here

Structural Systems Biology †

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• Provides uniform access from OGSA-based computing grid to existing bioinformatics databases.
• SQL-based Ad-hoc processing to integrate different web databases.

SQL based Ad-hoc Processing †

• Important genes should interact with other genes
• Important genes should have SNPs related to serious diseases
• Important proteins should interact with other proteins
   
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This processing enables to find out biologically important protein structures.

(For details, see: Y.Hirata et al. "GATS: grid-aided target selection for molecular simulation", Genome Informatics 2004,Yokohama,Japan)